Iron metabolism-related genes

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August undefined, 2024

WebMar 15, 2024 · These studies suggest that regulation of iron metabolism related gene expression is consequential for a cancer cell to survive the harsh conditions. Role of iron in the pathophysiology of cancer. Research has demonstrated the abnormality of iron homeostasis in several cancers including breast, ... WebOct 28, 2024 · Integrated analysis, cox regression and the least absolute shrinkage and selection operator (LASSO) method of 104 ferroptosis- and iron metabolism-related genes and HCC-related RNA sequencing were performed to identify HCC-related ferroptosis and iron metabolism genes. Results:

Development and validation of a prognostic prediction model for iron …

WebOct 6, 2024 · In this study, we identified candidate genes related to iron (Fe) and zinc (Zn) metabolism through gene expression analysis and correlated it with known QTL regions for GFeC/GZnC. WebSep 2, 2024 · The iron regulatory proteins (IRP1 and IRP2) are two cytoplasmic RNA-binding proteins involved in the mechanisms that control iron metabolism in mammalian cells. … how to sync ipod with iphone

A novel four-gene of iron metabolism-related and …

WebApr 13, 2024 · This study was designed to develop iron metabolism related molecular markers for Ferritin-1, BHLH-1 (Basic helix loop helix), or FER-like transcription factor protein and IRT-1 (Iron related transporter) genes using genome synteny with barrel medic ( Medicago truncatula ). WebMay 3, 2024 · Iron-related genes were further examined by FeGenie , and Fe-containing domains were characterized using Superfamily (v1.75) . Metagenome taxonomic profiling WebMay 28, 2024 · These iron-related COGs include ABC-type cobalamin/Fe 3+ -siderophore transport systems (Mann−Whitney Test, p- value = 0.011), NADPH-dependent ferric siderophore reductases (Mann−Whitney Test,... how to sync iphone to this computer

The Interplay between Intracellular Iron Homeostasis and ...

Genes Free Full-Text Role of Iron Metabolism-Related Genes in ...

WebMay 24, 2024 · Iron supplementation reduced morphological abnormalities of the mitochondria in skeletal muscle and increased the expression of genes related to mitochondrial ETC and energy metabolism in skeletal ... WebJan 4, 2024 · The iron metabolism-related genes were mostly implicated in retinol metabolism pathways, chemical carcinogenesis, and arachidonic and metabolism pathways, according to pathway enrichment analysis ( Figure 2E ). FIGURE 2 FIGURE 2. Functional enrichment analysis of dysregulated iron metabolism-related genes in TCGA-PAAD cohort. readly im browser lesenWebIron is an essential nutrient, yet excess iron can be toxic to cells. The uptake of iron by mammalian cells is post-transcriptionally regulated by the interaction of iron-response … readly go app

"WebObjective: Cardiac dysfunction caused by sepsis, usually termed sepsis-induced cardiomyopathy (SIC), is one of the most serious complications of sepsis, and ferroptosis can play a key role in this disease. In this study, we identified key cuproptosis- and ferroptosis-related genes involved in SIC and further explored drug candidates for the … " - Iron metabolism-related genes

Iron metabolism-related genes

WebIn this study, we identified four genes involved in iron metabolism and DNA methylation, whose expression levels are correlated with the prognosis of HCC, and used them to construct a prognostic model that can predict the prognosis of HCC, independent of … WebSep 9, 2024 · Iron metabolism is considered central for glioma tumorigenesis, tumor progression and tumor microenvironment, although key iron metabolism-related genes …

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WebApr 14, 2024 · The presence of Hg 2+ seriously inhibited the expression of functional genes relevant to the iron and sulfur metabolism of A. ferrooxidans ATCC 23270, and the expression of mercury-resistant genes was higher in earlier stages of growth than in the later stages of growth for the groups with aerobic iron and sulfur oxidation and the anaerobic … WebJul 1, 2015 · Besides the systemic regulation of iron metabolism mediated by hepcidin, cellular regulatory processes also occur. Cells are able to regulate themselves the expression of the iron metabolism-related genes through different post-transcriptional mechanisms, such as the alternative splicing, microRNAs, the IRP/IRE system and the …

WebMay 28, 2024 · Collectively, these data demonstrate that perturbation of iron metabolism-related genetic pathways in the root can impact rhizosphere composition, and that the … WebMay 22, 2024 · Sixteen iron metabolism-related gene sets (GO_IRON_ION_BINDING, GO_IRON_ION_IMPORT, GO_IRON_ION_TRANSPORT, GO_RESPONSE_TO_IRON_ION, HEME_BIOSYNTHETIC_PROCESS,HEME_METABOLIC_PROCESS, REACTOME_IRON_UPTAKE_AND_TRANSPORT, …

WebOct 22, 2024 · The molecular function of iron metabolism-related genes (IMRGs) is mainly enriched in active transmembrane transporter activity, and they mainly affect the biological process of response to oxidative stress. Ferroptosis and fluid shear stress and atherosclerosis pathways may be the critical pathways regulating iron metabolism in IPAH. WebNational Center for Biotechnology Information

WebFeb 2, 2024 · Hierarchical clustering of the aCGH results on iron metabolism‐related genes recognized differences between Brca1 Mut and the wild‐type in general (Figure S4A). Particularly marked were the changes in Tfr2 , which exhibited more amplification in chrysotile‐induced Brca1 Mut MMs (3/6) than that of the wild‐type (1/6) (Figures 1G and …

Webwe assessed their expression to reflect iron metabolism by integrating different omics data sources. The data expression profiles of asthma were searched in the Gene Expression Omnibus (GEO) database, and ... Differential expression analysis of iron transport-related genes in discovery and validation datasets (GSE67472 and GSE43696). b) The ... how to sync iphone to macbook proWebSep 15, 2024 · Iron is elementary for the maintenance of normal roles and homeostasis in cells. Accordingly, an imbalance in iron metabolism is related to the occurrence, growth, and metastasis of cancers closely (7). To be notable, iron metabolism plays double roles in … readly gift card offerWebAug 8, 2024 · Iron metabolism is crucial to hepatocellular carcinoma progression and is a key determinant of prognosis. Protein-protein interactions within the iron metabolism … readly im browserWebMay 3, 2024 · Key metabolic genes were universally present in all samples, including those involved in iron uptake and carbohydrate-active enzymes (CAZymes). We further examined the community-level... how to sync iphone to ipad contacts readly homepageWebOct 18, 2024 · Iron metabolism-related genes reveal predictive value of acute coronary syndrome Introduction. Iron deficiency has detrimental effects in patients with acute … readly im auslandWebSep 2, 2024 · The iron regulatory proteins (IRP1 and IRP2) are two cytoplasmic RNA-binding proteins involved in the mechanisms that control iron metabolism in mammalian cells. They modulate the expression of iron-related proteins at a post-transcriptional level by binding to specific iron regulatory elements (IREs) on their mRNAs. readly gutscheincode